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PreSens Optical Sensors: Advanced sensors for nearly any application

Major pharmaceutical companies, smaller organizations, and academia have all improved their bioprocess development with PreSens sensors. Using these non-invasive measurement systems, no more time consuming sampling is necessary and they allow simultaneous monitoring of multiple samples. A wide variety of disposables with integrated, pre-calibrated sensors is available; they are ready-to-use to obtain maximum work efficiency and allow monitoring the important culture parameters O2, pH and CO2 in every step of process development. 

We offer a wide variety of sensors and transmitters. If your solution is missing, please send us a message!

Sensor Probes

Sensor probes for oxygen, pH and carbon dioxide are designed to measure in small compartments or in very large vessels. They are applicable for micro-liter scale to production scale. Different probes for research, medical and industrial applications are offered. Features include:

  • Non-invasive sensors
  • Microsensors
  • Different measurement ranges
  • Sensors for liquid and gas
  • Calibration-free probes

Oxygen Sensor Formats

Oxygen Sensor Spots

web teaser sensor spots 29Sensor spots (SP) are the most versatile version of non-invasive optical oxygen sensors. They are attached to the inner surface of any transparent vessel:

  • Cultivation bags
  • Spinners
  • Glass reactors

The transmitter with its optical fiber can be fixed opposite the sensor spot by using our accessories which can be adapted for nearly all kinds of vessels.

It is also possible to use oxygen sensor spots in a tradiational bioreactor probe format.

Oxygen Flow-Through Cells

web teaser flow through cell 11The flow-through oxygen minisensor (FTC) is a miniaturized chemical optical sensor integrated in a flow-through cell. It is connected to the transmitter by an optical fiber. A glass tube with an inner diameter of 2 mm is coated with an optical oxygen sensor at its inner wall. The volume for liquid inside the FTC is about 100 (±10) microliter. The standard flow-through cell can be easily connected via Luer-Lock adapters to external tubings.

Needle-Type Oxygen Sensors

web teaser ntho2 cat copy 17Needle-type oxygen microsensors are perfectly suited for measuring oxygen distribution profiles in sediment and biofilms with a high spatial resolution of less than 50 µm. The oxygen-sensitive tip of an optical fiber is protected inside a stainless steel needle. This design is optimal for easy penetration of tissue, septum rubber or packaging materials. After penetration the sensor tip is extended for measurement.

Implantable Oxygen Sensors

web teaser impo2 13Implantable probes are the miniaturized fiber optic oxygen sensors designed for various customized applications. The tiny probe has a tip size of < 50 µm (TS) to 140 µm (TF) while the outer diameter ranges from 140 µm to 900 µm.
The microsensor tip is not mounted in any additional housing. The bare glass fiber tip can be mounted to your own housings, steel tubes and micro respirometer chambers etc. The small outer diameter even allows insertion into implantable Venlon-tubes. Moreover the microsensor can be deployed in sealed containers to measure the oxygen content directly.

pH Sensor Formats

pH Sensor Spots

web teaser sensor spots 31Sensor Spots (SP) are the most versatile version of non-invasive pH sensors. They are attached to the inner surface of any transparent vessel:

  • Shake flasks & spinners
  • Tubes & petri dishes
  • Cultivation bags

The transmitter with its optical fiber can be fixed opposite the sensor spot using our accessories (see our accessories brochure) which can be adapted for nearly all kinds of vessels.

pH Flow-Through Cells

web teaser ftc hp8 12The flow-through pH minisensor (FTC) is a miniaturized fiber chemical optical sensor integrated in a flow-through cell. It is connected to the transmitter by an optical fiber. The volume of liquid inside the FTC is about 250 microliters. The standard flow cell can be easily connected via Luer-Lock adapters to external tubing. The FTC is beta-irradiated and pre-calibrated.

Carbon Dioxide Sensor Formats

Carbon Dioxide Sensor Spots

web teaser sensor spots 30Sensor spots (SP) are the most versatile version of CO2 sensors. They are attached to the inner surface of any transparent vessel:

  • Glass bioreactor
  • Sight glass
  • Flasks

The optical fiber of the transmitter can be fixed opposite the SP by using our accessories (see accessories brochure) which can be adapted for nearly all kinds of vessels.

Carbon Dioxide Flow-Through Cell

web teaser co2 ftc-cd1 10The flow-through cell carbon dioxide mini-sensor (FTC-CD1) is a miniaturized chemical optical sensor integrated in a flow-through cell. The cell is built from a 3 cm glass tube with 7 mm outer diameter with a CO2 sensor integrated and a customized holder (FTC-Holder) fixing the polymer optical fiber for signal transduction. The cell is autoclavable.

Carbon Dioxide Dipping Probe

web teaser dipping probe 14The CO2 dipping probe is a chemical optical sensor based on 2 mm polymer optical fiber (POF). The sensor membrane is fixed at the tubing end of the optical fiber connected to the transmitter. It is the solution for invasive measurements and monitoring.

Transmitter Options

Transmitters are available for research and industrial environments. Each comes with software to facilitate data acquisition and evaluation.

  • Single & Multi-channel systems
  • Software included
  • For industrial and research applications
  • One calibration for a multitude of sensor probes

Transmitters for Oxygen Sensors

Fibox 4 / Fibox 4 trace

web teaser FB4 Product 03The Fibox 4 and Fibox 4 trace are completely stand-alone fiber optic oxygen transmitter. The robust, light weighed housing is splash proof and allows easy handheld use even under harsh conditions. Like the other PreSens oxygen meters the Fibox 4 and Fibox 4 are temperature compensated systems and have additional automatic compensation for pressure and salinity. The new sensor and calibration management system allows easy sensor handling: Data of up to 100 sensors can be stored and with the transmitters´ integrated barcode reader sensor identification and calibration can be realized by performing just one scan. The PreSens Datamanager permits easy data transfer between the Fibox 4 / Fibox 4 trace and the PC. An optional extended and database supported PC software allows controlling up to 10 devices simultaneously so measurement networks can be set up.

Fibox 3 / Fibox 3 trace

web teaser fibox3 fibox3 trace 09The Fibox 3 and Fibox 3 trace are precise fiber optic oxygen transmitters. They are temperature compensated and used with oxygen sensors based on a 2 mm optical fiber. A PC is connected to run the easy-to-use software. On top, analogue outputs and a trigger input are integrated.
Fibox 3 is used for sensor coatings type PSt3 (detection limit 15 ppb,
0 - 100 % oxygen). Fibox 3 trace additionally works with the trace oxygen sensor coating type PSt6 (detection limit 1 ppb, 0 - 4.2 % oxygen).

Fibox 3 LCD trace

web teaser Fibox 3 LCD trace 1 04The Fibox 3 LCD trace is a stand-alone fiber optic oxygen transmitter. It is temperature compensated and used with oxygen sensors based on a 2 mm optical fiber. It is a portable instrument with a rechargeable battery and a built-in data-logger. It can be controlled via an integrated, programmable LCD control panel. Alternatively, the Fibox 3 LCD trace can be connected to a PC for measurement. Fibox 3 LCD is used for sensor coatings type PSt3 (detection limit 15 ppb, 0 - 100 % oxygen) and type PSt6 (detection limit 1 ppb, 0 - 4.2 % oxygen).

Oxy-4 mini/trace

web teaser oxy4 mini 09The OXY-4 mini and OXY-4 trace are precise 4-channel fiber optic oxygen transmitters. They are used with oxygen sensors based on a 2 mm optical fiber. A PC is connected to run the easy to use software. OXY-4 mini is used for sensor coatings type PSt3 (0 - 100 % oxygen). OXY-4 trace additionally works with the trace oxygen sensor coating type PSt6 (detection limit 1 ppb, 0 - 4.2 % oxygen).

Oxy-10 mini/trace

web teaser oxy10 mini 09The OXY-10 mini and the OXY-10 trace are precise 10-channel fiber optic oxygen transmitters. They are used with oxygen sensors based on a 2 mm optical fiber. A PC is connected to run the easy-to-use software. OXY-10 mini is used for sensor coatings type PSt3 (0 - 100 % oxygen). OXY-10 trace additionally works with the trace oxygen sensor coating type PSt6 (detection limit 1 ppb, 0 - 4.2 % oxygen).

EOM-O2 mini

web teaser eom boards 05The electro-optical module EOM-O2-mini is a precise OEM solution for non-invasive oxygen sensor spots. Self-contained test procedures of every individual system ensure high product safety. EOM modules are offered for sensor coatings type PSt3 (0 - 100 % oxygen) and trace oxygen sensor coating type PSt6 (detection limit 1 ppb, 0 - 4.2 % oxygen).

Microx TX3 and Microx TX3 trace

web teaser tx3 tx3 trace 07The Microx TX3 and Microx TX3 trace are precise micro fiber optic oxygen transmitters. They are temperature compensated and used with oxygen microsensors based on a 140 µm optical fiber. A PC is connected to run the easy-to-use software. On top, analogue outputs and a trigger input are integrated. Microx TX3 is used for microsensors type PSt1 (detection limit 20 ppb,  0 - 50 % oxygen). Micox TX3 trace additionally works with the trace oxygen microsensor type TOS7 (detection limit 1 ppb, 0 - 3 % oxygen).

Oxy-4 Micro

web teaser oxy 4 micro 07The OXY-4 micro is a precise 4-channel micro fiber optic oxygen transmitter. It is used with oxygen microsensors based on a 140 µm optical fiber. A PC is connected to run the easy-to use software. OXY-4 micro is used for microsensors type PSt1 (detection limit 20 ppb, 0 - 50 % oxygen).

Oxy-10 Micro

web teaser oxy 10 micro 07The OXY-10 micro is a precise 10-channel micro fiber optic oxygen transmitter. It is used with oxygen microsensors based on a 140 µm optical fiber. A PC is connected to run the easy-to-use software. OXY-10 micro is used for microsensors type PSt1 (detection limit 20 ppb, 0 - 50 % oxygen).

Transmitters for pH Sensors

pH-1 mini

web teaser ph1 mini 07The pH 1-mini is a precise fiber optic pH transmitter. It is temperature compensated and used with pH sensors based on a 2 mm optical fiber. A PC is connected to run the easy-to-use software. On top, analogue outputs and a trigger input are integrated.

pH-4 mini

web teaser ph4 mini 06The pH-4 mini is a precise 4-channel fiber optic pH transmitter. It is used with pH sensors based on a 2 mm optical fiber. A PC is connected to run the easy-to-use software.

pH-10 mini

The pH-10 mini is a precise 10-channel fiber optic pH transmitter. It is used with pH sensors based on a 2 mm optical fiber. A PC is connected to run the easy-to-use software.

 

EOM-pH mini

web teaser eom 04The electro-optical module EOM-pH-mini is a precise OEM solution for non-invasive pH sensor spots. Validation and customization of the integrated software is offered. EOM-pH-mini supports patented DLR based pH sensors.

pH-1 micro

web teaser pH1 micro 08The pH-1 micro is a precise micro fiber optic pH transmitter. It is temperature compensated and used with pH microsensors based on a 140 µm optical fiber. A PC is connected to run the easy-to-use software. On top, analogue outputs and a trigger input are integrated.

pH-4 micro

web teaser ph4 micro 08The pH-4 micro is a precise 4-channel micro fiber optic pH transmitter. It is used with pH microsensors based on a 140 µm optical fiber. A PC is connected to run the easy-to-use software.

Transmitters for Carbon Dioxide Sensors

pCO2-mini

web teaser pco2 mini 10The pCO2 mini is a precise fiber optic CO2transmitter. It is temperature compensated and used with CO2 sensors based on a 2 mm optical fiber. A PC is connected to run the easy-to-use software. pCO2 mini is additionally equipped with an analogue out and a trigger in. CO2 sensors are optimized for physiological solutions.

EOM-CO2-mini

web Teaser EOM-CO2 neu 02The electro-optical module EOM-CO2-mini is a precise OEM solution for non-invasive CO2measurements. Assembled according to ISO 9001:2008 they deliver certified quality. In addition, validation and customization of the integrated software is offered. EOM-CO2-mini supports patented DLR based CO2sensors.

Speciality Systems

Optrode Dual for pH and Oxygen

web teaser OptordeDual 04The Optrode Dual™ converts the reading of chemical optical sensors to electrochemical signals (ECS). It can be connected to the electrode input of a conventional controller and expands its functionality to work with chemical optical sensors.

Shake Flask Reader

web sfr flasks 07The SFR - Shake Flask Reader monitors oxygen and pH in up to 9 shake flasks simultaneously. It fits in nearly all standard shakers. The  corresponding ready-to-use flasks contain pre-calibrated sensor spots. The system monitors non-invasively through the transparent bottom of the flask. Different types and sizes of flasks are available. Plastic flasks contain pre-calibrated oxygen and pH sensors. They are ready-to-use for one cultivation. Glass flasks are equipped with autoclavable oxygen sensors.

Visit the Shake Flask Reader detail page.

SensorDish Reader

web titel hand on sdr 13The SDR SensorDish® Reader is a small 24-channel reader for non-invasive detection of oxygen and pH in multidishes (SensorDishes®). These contain a sensor spot at the bottom of each well. They are read out non-invasively through the transparent bottom. SensorDishes® for oxygen (OxoDish®) and pH (HydroDish®) are available in the 24-well and 6-well format. Read out of oxygen sensors integrated in glass vessels for respiration monitoring is also possible. The SensorDish® Reader can be used in incubators and on shakers and is thus the ideal tool for cell cultivation.

Visit the SensorDish Reader detail page.

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Applikon's specialists can work with you to find the right PreSens sensors to meet your process needs. You can request additional information about PreSens sensors directly from your local representative.

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